SCIENTIFIC LITERATURE

• Rationale for mechanism of DAVANAT" action.
• Enhanced biorecognition and internalization of HPMA copolymers containing multiple or multivalent carbohydrate side-chains by human hepatocarcinoma cells.
• Enhanced clearance of topoisomerase I inhibitors from human colon cancer cells by glucuronidation.
• Regulation of tumour drug delivery by blood flow chronobiology.
• Serum, urine and peritoneal fluid levels of 5-FU following intraperitoneal administration.
• Opsonising immunoglobulins and mannan-binding lectin in chronic lymphocytic leukemia.
• Calreticulin binding affinity for glycosylated laminin.
• Transfer of free polymannose-type oligosaccharides from the cytosol to lysosomes in cultured human hepatocellular carcinoma HepG2 cells.
• NCI Grant to Study Colorectal Cancer Metastasis.
• Why are carbohydrate polymers more efficient in binding receptors on cancer cells?
• What types of Lectins exist?
• Why is sugar important to protein? The process is called glyco-protein.
• Why are glycans important to protein folding?
• Why can the lectin mannose binding protein reduce infection?
• A new cancer gene (lectin) that recognizes mannose.
• Why does DAVANAT" recognize mannan receptors on living cells?
• Mannan receptors are present on colon cancer cells.
• US statistics for cancer patients distribution.